Dave Brown writes:

Working with the Multidisciplinary Association for Psychedelic Studies (MAPS) for the past four years as their guest editor has been an extremely exciting and tremendously fruitful endeavor for me. It’s a great joy to see how MDMA can help people suffering from posttraumatic stress disorder (PTSD), how LSD can help advanced-stage cancer patients come to peace with the dying process, and how ibogaine can help opiate addicts overcome their addiction. There appears to be enormous potential for the development of psychedelic drugs into effective treatments for a whole range of difficult-to-treat psychiatric disorders.

However, as thrilled as I am by all the new clinical studies exploring the medical potential of psychedelic drugs, I still long for the day when our best minds and resources can be applied to the study of these extraordinary substances with an eye that looks beyond their medical applications, toward their ability to enhance human potential and explore new realities.

This article explores these possibilities. But first, let’s take a look at how we got to be where we are.

Keep reading.

POSTED FROM DISINFO.COM

The body is a highly complicated biological machine, and the brain is no exception. In fact, our brain is so subtle and sophisticated, even today’s science has a hard time keeping up with it. One thing we do understand, however, is that some things tend to keep our mental performance at a maximum.

Brain workouts”, such as doing crossword puzzles or studying a foreign language, are one clearly demonstrated way to keep our minds sharp, especially as we age. Getting proper nutrition is another. Here are some crucial nutrients that you want to include in your diet in order to make sure your memory, focus and linguistic aptitude stay healthy:

Vitamin D

We often think of vitamins D as simply the vitamin that makes our bones strong; however, it actually plays a big part in our mental functioning. Vitamin D is effective in stimulating nerve growth, making it essential for cognition, reflexes and perception. In addition, vitamin D receptors in the brain play a role in the synthesis of neurotransmitters, the chemicals that communicate between the brain and the rest of the body.

A deficiency of vitamin D has been linked to reduced cognitive abilities, notably a slowdown in processing mental data.

Vitamin E

You may already think of vitamin E as an antioxidant, or an agent that stops the body from falling victim to free radicals—those chemically unstable molecules that cause the body to break down. In the brain, this often means developing degenerative diseases, such as Alzheimer’s and dementia.

As you obviously don’t want a vitamin E deficiency, be sure to eat plenty of nuts, seeds, olives and other foods rich in this vitamin.  You should also consider taking vitamin E supplements to maintain a stable mind in late life, especially if you know Dementia, Alzheimer’s and Parkinson’s runs in your family.

Vitamin C

Like vitamin D, vitamin C is water soluble and a necessary element in synthesizing neurotransmitters.  In the case of vitamin C, the chief neurotransmitter at stake is norepinephrine, a chemical that we need for vital survival reflexes and other brain functions.  Not only that, it keeps our moods stable, so an adequate supply of vitamin C ensures that we feel and think our best.

On top of eating plenty of citrus fruits, you can take supplements as a backup; however, consult your doctor to determine the appropriate dosage, as an overdose of vitamin C can cause an array of stomach woes and, over time, even kidney stones.

Vitamin B-12

Yet another important brain chemical synthesizer, B12 is a major player in the functioning of the central nervous system and the production of new red blood cells.  Older subjects with low intake of vitamin B12 have demonstrated to have slower cognition, decreased spatial orientation and poor memory.

Vitamin B12 is easy to get from a variety of meat and dairy items, such as red meat, fowl, milk and eggs. For vegans in particular, this is one clear case where supplements are encouraged.

In addition to maintaining a diet and supplement regimen that gives you the “brain food” you need, there are other nutrients that are known to promote brain functioning.  Gingko biloba extract, for example, helps with focus and concentration, and can only be taken in supplemental form.

Although we should always be skeptical of sudden fads, there truly are mental superfoods, such as the fermented soy product natto. However you choose to get your daily intake of essential vitamins, to make the most of out of your latter years, be sure to feed your head.

POSTED FROM LEARNING MIND

It’s the most fundamental question possible: Why is there something, instead of nothing? When the universe was created, theory says that matter and antimatter should have been created in equal measure, and we know that when these two types of particles meet they react by annihilating one another. By all accounts, the universe should never have been able to get started, should have wiped itself out immediately. So, what happened? Was there less antimatter created than we predicted, or did we somehow avoid the annihilation process? Why does the universe contain matter at all? One way of investigating these questions is to study neutrinos, and for several years the “EUROnu” project has been trying to decide the best way of doing so. This month, the commission presented its findings at CERN: they want to build the Neutrino Factory.

This refreshingly acronym-free device creates beams of neutrinos by smashing protons into a solid target, creating muons which reliably decay into neutrinos. The beam would be fired roughly downwards, traveling 2,000 kilometers or more to the receiving end. The emitter will probably be at CERN, in Switzerland, though the receiver has been proposed to go anywhere from Japan to Italy to the UK. Regardless, upon arrival the beam of neutrinos will be analyzed for its content: what proportions of the three types of neutrinos are found, and how they compare to the proportions in the beam when it left the emitter. Such investigations into the interconversion of neutrinos and anti-neutrinos could shed light on the nature of antimatter (among other things).

The EUROnu group considered three proposals for performing tests similar to this, and determined that the Neutrino Factory would produce the most accurate results. However, it is also the most expensive option by far. Their cost estimates put the facility between 6.1 and 8.1 billion dollars. The other two options, known as the Super Beam and Beta Beam, might cost about a quarter or a third as much, respectively.

One major factor that influenced their decision was a staged approach to constructing the Neutrino Factory, each step of which could be useful in its own right. The vSTORM project would function as a prototype for the Neutrino Factory and result in a storage ring full of circulating muon particles. This ring could itself be used for several high-level experiments, including the search for sterile neutrinos, a theoretical type of particle that ignores all properties of the standard model of physics, save gravity.

They do hedge their bets, claiming that if certain other projects are brought to fruition independently, their recommendation might change. For instance, if the MEMPHYS detector were to be built elsewhere, probably for investigation of proton lifetimes, they could justify creating the Super Beam as a minor addition. This would make the Super Beam option just another step on the way to the Neutrino Factory.

To put the proposal into context, the Large Hadron Collider, an infamously long and expensive project in its own right, cost less than the commission’s upper-bound estimate for the Neutrino Factory. Since the LHC only stretches into a paltry two countries, this Europe-spanning neutrino beam could be a truly international project — not that the intervening countries could do much to stop the beam, should they want to.

CERN recently updated its stance toward fundamental research into particle physics, expressing optimism about another proposed neutrino gun, this one to fire the particles along the 1,300-kilometer span between Fermilab in Illinois (aboveimage) and a mine in South Dakota. There’s no guarantee that the Neutrino Factory will actually be built, or indeed if any of the three options will see the light of day, but here we have a reasoned argument in favor of what might be humanity’s next great foray into particle physics.

The LHC has and will continue to investigate the nature of gravity, why matter coalesces to allow us to exist. The Neutrino Factory could investigate why that matter even exists in the first place.

POSTED FROM EXTREME TECH


All of the releases under Dominoes Falling Productions will always be free…however your help and support is needed, in the funding of a camera. indiegogo.com/projects/support-dfp-with-a-camera/x/3561392

A Good Feeling (2013) is a short film by Dominoes Falling Productions, featuring Joe Rogan, Jacque Fresco, MLK, Captain Picard & Pretty Lights with visual footage from the films ‘Blueberry’ (2004) & ‘I, Pet Goat II’ (2012).

dominoesfallingproductions.com/
facebook.com/DominoesFallingProductions
twitter.com/DominoesFalling
vimeo.com/dominoesfallingprods/
youtube.com/user/DominoesFallingProds

Links for sources used:

heliofant.com/ ~ I, Pet Goat II (2012)
en.wikipedia.org/wiki/Blueberry_(film) ~ Blueberry (2004)
youtube.com/watch?v=Oehry1JC9Rk ~ Martin Luther King’s Last Speech
youtube.com/watch?v=ui6g23ygov8 ~ Captain Picard Promotes A Resource Based Economy
joerogan.net/podcasts/ ~ The Joe Rogan Experience Podcast
youtube.com/watch?v=42RYbA_3ImU ~ Jacque Fresco – The Venus Project | London Real Podcast

Music (in order):
soundcloud.com/hiatus/dawn ~ Hiatus – Dawn
soundcloud.com/prettylights/pretty-lights-finally-moving ~ Pretty Lights – Finally Moving

With thanks to Andy Johnson for the cover design.

“Saying people can’t live without government is like saying animals can’t live without farms.”

The 2007-2008 financial crisis, you might think, was an unpredictable one-time crash. But Didier Sornette and his Financial Crisis Observatory have plotted a set of early warning signs for unstable, growing systems, tracking the moment when any bubble is about to pop. (And he’s seeing it happen again, right now.)

Biologists at University College London say they now know why cancerous cells group together and spread to different parts of the body. And shockingly, it appears that the malignant cells are migrating by literally chasing healthy cells that are trying to get away.

Scientists already understood that malignant cells interact with healthy cells to move around the body during metastasis. The cancer cells recruit healthy cells and use them to travel long distances, resulting in a secondary tumor. But prior to this study, scientists weren’t entirely sure how this process takes place — or how this information could be used to develop new cancer fighting therapies.

The proposed mechanism is called chase-and-run — and it’s an apt description. By studying embryonic cells called neural crest cells (which have invasive properties similar to cancer cells) and placode cells (healthy cells that contribute to sensory organs) the researchers got a hint as to what might be going on.

The researchers, a team headed by Roberto Mayor, noticed that neural crest cells start to chase placode cells when they’re placed beside them. The placode cells produce a chemical attractant that the neural crest cells find irresistible (a process called chemotaxis involving PCP and N-cadherin signalling).

But not resigned to their fate, placode cells try to get away — what the researchers call escape behavior. Regrettably, it’s this escape behavior that then causes the invasive neural crest cells to move around the body, a process now known as directional collective migration.

Now, it’s important to remember that this is not cancer per se — but the researchers are confident that some cancers works according to this chase-and-run principle; healthy cells try to escape from tumor cells, only to be followed around the body by malignant cells.

“We use the analogy of the donkey and the carrot to explain this behaviour: the donkey follows the carrot, but the carrot moves away when approached by the donkey,” noted Mayor through a release. “Similarly the neural crest cells follow the placode cells, but placode cells move away when touched by neural crest cells.”

The discovery could pave the way for alternative cancer treatments — future therapies that can work to disrupt the process of interaction between malignant and healthy cells.

And indeed, this would be important as most cancer deaths are not due to the rise of the primary tumor, but on account of secondary tumors originating from the first malignant cells.

Consequently, the researchers say it will be “relatively easy” to develop drugs that interfere with this interaction.

Well, nothing is easy in cancer research — but let’s hope this team is on to something.

It’s also worth noting that the mechanism does nothing to explain why the cancer arises in the first place.

Read the entire study at Nature Cell Biology: “Chase-and-run between adjacent cell populations promotes directional collective migration.”

POSTED FROM IO9

We’ve seen plenty of phones that support wireless charging, but it’s still not a common feature on most phones. Over on Instructables, user Harari shows you how to add a wireless charging system to just about any cell phone that charges with a USB.

The hack uses an old Palm Touchstone charger, and a handful of cheap coils and wires. When you’re done, you’ll be able to simply rest your phone on the Touchstone and it should charge. It’s similar to a hack we’ve seen before, but the end result is a bit cleaner and functional. As with any power-related hack, you’ll want to proceed at your own risk, but if you have an old phone you want to try this out on it’s certainly worth a shot. Head over to Instructables for the full guide and a ton of pictures.

POSTED FROM LIFE HACKER